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Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin

Name: Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin
SKU: ICH1084
Price: 150 USD
Availability: InStock

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SKU

ICH1084

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$150.00 - $23,460.00

Bulk anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10)

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Product Specific Citations

Rodriguez-Baena, FJ et al. Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases. Cancer Cell, 2025, 43, 3: 413 - 427.e9

Species Reactivity

Mouse

Target

CTLA-4

Concentration

1.0 - 5.0 mg/ml

Isotype

Syrian Hamster IgG

Host

Syrian Hamster

Use

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Applications

Western Blot, Blocking, ELISA, Flow Cytometry

Storage

anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Purification Method

This monoclonal antibody was purified using Protein A

Specificity

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4

Shipping Conditions

Blue ice

Background

CTLA-4 (CD152) is an inhibitory checkpoint receptor that outcompetes CD28 for B7 ligands to restrain T-cell activation and enforce peripheral tolerance. Clone 9H10 is a Syrian hamster IgG monoclonal antibody to CTLA-4 in the mouse, validated for Western blot, blocking, ELISA and flow cytometry. Anti-CTLA-4 9H10 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. As a non-therapeutic, research-use-only (RUO) reagent, 9H10 provides reproducible performance for checkpoint-blockade and tumour-immunology studies in the mouse.

Other Names

Ctla4, Cytotoxic T-lymphocyte protein 4, CD152

Clone

9H10

Uniprot

P09793

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Antigen Distribution

Activated T cells

Immunogen

Mouse CTLA-4-human IgG1 fusion protein

Aggregation

Aggregation level ≤ 5%

Antibodies Against The Same Target

Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [UC10-4F10-11] (ICH1085), Anti-CTLA-4 In Vivo Antibody - Low Endotoxin [9D9] (ICH1096), Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin [9D9] (ICH1096UL)

Related Antibody

Anti-CTLA-4 In Vivo Antibody - Ultra Low Endotoxin [9H10] (ICH1084UL)

More Information

Bio X Cell:

ICH1084 is up to 47% cheaper for industry than the equivalent low endotoxin product (BE0131) and up to 39% cheaper for the ultra-low endotoxin product (BP0131) from Bio X Cell. The low endotoxin version is up to 19% cheaper for academia, whilst the ultra-low endotoxin product is up to 7%. Product Benefits:

ichorbio's anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is manufactured in a cGMP compliant facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from Bio X Cell at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.

Target:

CTLA-4

Isotype Control:

Syrian Hamster IgG Isotype Control for In Vivo – Low Endotoxin [ICH2253]

Antibodies against the same target:

Alternative Names: