Skip to content
  • Login / Register
  • Cart / $0.00
    • No products in the cart.

  • Add anything here or just remove it...
ichorbioichorbio
  • Products
    • Immune Checkpoint Molecules
      • CD40 Reagents
      • CD70 Reagents
      • CD86 Reagents
      • CTLA-4 Reagents
      • LAG-3 Reagents
      • PD-1 Reagents
      • PD-L1 Reagents
    • Nucleic Acid Stains
    • Research Biosimilars – All Products
    • Isotype Controls
    • Type I & Type II Interferons
    • Ultra-Pure Detergents
    • Mouse Immune Cell Depletion Antibodies
  • About Us
  • Resources
    • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
    • Amazon Vouchers for Reviews
    • How to Write a Great Life Science Paper
  • Distribution Network
  • Contact Us
  • Cart

    No products in the cart.

Home / Recombinant Proteins
Filter

Recombinant Human PD-L1 [ICH3060]

$519.00 – $3,537.00

Clear
Recombinant Human PD-L1 [ICH3060]

— OR —

SKU: ICH3060 Category: Recombinant Proteins
Browse
  • Antibodies
    • Biosimilar Antibodies
    • Isotype Controls
    • Low Endotoxin
    • Ultra Low Endotoxin
  • Applications
    • Blocking
    • CODEX
    • CyTOF
    • Dot Blot
    • ELISA
    • ELISpot
    • Flow Cytometry
    • Flow Cytometry (intracellular)
    • Functional Assays
    • IHC (Frozen)
    • IHC (Paraffin)
    • ImmunoCytoChemistry
    • Immunofluorescence
    • Immunoprecipitation
    • In Situ Hybridization
    • In Vivo Depletion
    • IP-Mass Spectrometry
    • Neutralization
    • Western Blot
  • Conjugated
    • APC
    • Biotin
    • DyLight 488
    • DyLight 550
    • DyLight 594
    • DyLight 633
    • DyLight 650
    • DyLight 680
    • DyLight 755
    • DyLight 800
    • FITC
    • PE
    • PE/Cy7
    • PerCP
  • Gel Stain
  • Recombinant Proteins
  • Species Reactivity
    • anti-bovine
    • anti-chicken
    • anti-human
    • anti-mouse
    • anti-rat
    • Monkey
  • Description
  • Additional information
  • Reviews (0)

Bulk Recombinant Human PD-L1 [ICH3060]

 

Product Benefits:
ichorbio’s Recombinant Human PD-L1 is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information.
Expression Host:
NSO Cells
Formulation:
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Background:
PD-1 is a 50-55 kD member of the B7 Ig superfamily. PD-1 is also a member of the extended CD28/CTLA-4 family of T cell regulators and is suspected to play a role in lymphocyte clonal selection and peripheral tolerance. The ligands of PD-1 are PD-L1 and PD-L2, and are also members of the B7 Ig superfamily. PD-1 and its ligands negatively regulate immune responses. PD-L1, or B7-Homolog 1, is a 40 kD type I transmembrane protein that has been reported to costimulate T cell growth and cytokine production. The interaction of PD-1 with its ligand PD-L1 is critical in the inhibition of T cell responses that include T cell proliferation and cytokine production. PD-L1 has increased expression in several cancers. Inhibition of the interaction between PD-1 and PD-L1 can serve as an immune checkpoint blockade by improving T-cell responses In vitro and mediating preclinical antitumor activity. Within the field of checkpoint inhibition, combination therapy using anti-PD1 in conjunction with anti-CTLA4 has significant therapeutic potential for tumor treatments. PD-L2 is a 25 kD type I transmembrane ligand of PD-1. Via PD-1, PD-L2 can serve as a coinhibitor of T cell functions. Regulation of T cell responses, including enhanced T cell proliferation and cytokine production, can result from mAbs that block the PD-L2 and PD-1 interaction..
Other Names:
B7 Homolog 1, B7-H, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7-H1
Purity:
>90% by SDS-PAGE and analyzed by silver stain.
Biological activity:
The biological activity of Human B7-H1 was determined by its ability to compete with biotin labeled in rhB7-H1 for the binding of rmPD-1/Fc in a functional ELISA.
Endotoxin level:
<1.0 EU/ug as determined by the LAL method
Amino acid sequence:
ft vtvpkdlyvv eygsnmtiec kfpvekqldl aalivyweme dkniiqfvhg eedlkvqhss yrqrarllkd qlslgnaalq itdvklqdag vyrcmisygg adykritvkv napynkinqr ilvvdpvtse heltcqaegy pkaeviwtss dhqvlsgktt ttnskreekl fnvtstlrin tttneifyct frrldpeenh taelvipelp lahppnertd iegrmdpksc dkthtcppcp apellggpsv flfppkpkdt lmisrtpevt cvvvdvshed pevkfnwyvd gvevhnaktk preeqynsty rvvsvltvlh qdwlngkeyk ckvsnkalpa piektiskak gqprepqvyt lppsrdeltk nqvsltclvk gfypsdiave wesngqpenn ykttppvlds dgsfflyskl tvdksrwqqg nvfscsvmhe alhnhytqks lslspgk.
State of Matter:
Lyophilized.
Storage & Stability:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Predicted Molecular Mass:
The predicted molecular weight of Recombinant Human B7-H1 is Mr 52 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 70-75 kDa.
N-terminal Sequence Analysis:
Phe19
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures
Size:

0.1mg, 1mg

Reviews

There are no reviews yet.

Be the first to review “Recombinant Human PD-L1 [ICH3060]” Cancel reply

Your email address will not be published. Required fields are marked *

Related products

+
Quick View

Recombinant Proteins

Recombinant Mouse CD80 [ICH3071]

$490.00
+
Quick View

Recombinant Proteins

Recombinant Mouse PD-L1 [ICH3058]

$490.00
+
Quick View

Recombinant Proteins

Recombinant Human CD86 [ICH3062]

$504.00
+
Quick View

Recombinant Proteins

Recombinant Mouse CD86 [ICH3072]

$504.00
About us

From Oxford, United Kingdom - ichorbio supplies the best antibodies for in vivo research. Our in vivo antibodies are sold for the purposes of research only, not for therapeutic or diagnostic use.

ichorbio Ltd, Grove Business Park, Downsview Road, Wantage OX12 9FF

Our best selling in vivo antibodies:

  • CTLA-4 in vivo antibody (9H10)
  • CTLA-4 in vivo antibody (9D9)
  • HLA-DP in vivo antibody (B7/21)
  • IFNAR1 in vivo antibody (MAR1-5A3)
  • PD-1 in vivo antibody (RMP1-14)
  • PD-L1 in vivo antibody (10F.9G2)
  • TNF-alpha in vivo antibody (TN3-19.12)

Our best selling Research Grade Biosimilars:

  • Atezolizumab - Research Grade
  • Avelumab - Research Grade
  • Eculizumab - Research Grade
  • Ipilimumab - Research Grade
  • Nivolumab - Research Grade
  • Ofatumumab - Research Grade
  • Pembrolizumab - Research Grade
  • A Beginner’s Guide to Writing a Life Science Paper
  • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
  • Terms & Conditions
  • Privacy Policy
Copyright 2021 © ichorbio .
  • Products
    • Immune Checkpoint Molecules
      • CD40 Reagents
      • CD70 Reagents
      • CD86 Reagents
      • CTLA-4 Reagents
      • LAG-3 Reagents
      • PD-1 Reagents
      • PD-L1 Reagents
    • Nucleic Acid Stains
    • Research Biosimilars – All Products
    • Isotype Controls
    • Type I & Type II Interferons
    • Ultra-Pure Detergents
    • Mouse Immune Cell Depletion Antibodies
  • About Us
  • Resources
    • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
    • Amazon Vouchers for Reviews
    • How to Write a Great Life Science Paper
  • Distribution Network
  • Contact Us
  • Login

Login

Lost your password?

Register

A password will be sent to your email address.

Your personal data will be used to support your experience throughout this website, to manage access to your account, and for other purposes described in our privacy policy.

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok