PD-1/PD-L1 inhibitor
Product Benefits:
ichorbio’s PD-1/PD-L1 inhibitor (BMS202 hydrochloride) is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Background:
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 (free base) binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
CAS Number:
1675203-84-5
Molecular Weight:
455.97
Formula:
C25H30ClN3O3
Solubility:
DMSO: 30 mg/mL(71.51 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage:
Store at -80°C
Other remarks:
For obtaining a higher solubility, please warm the tube to 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.
Purity:
Over 99%
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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