Nivolumab Biosimilar – Research Grade [ICH4009]
$690.00 – $4,000.00
Bulk Nivolumab Biosimilar – Research Grade
Product Benefits:
ichorbio’s Nivolumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Size:
ichorbio’s research grade nivolumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our nivolumab biosimilar – please contact us for pricing.
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our nivolumab biosimilar – please contact us for pricing.
Target:
PD-1
Clone:
n/a
Isotype:
IgG4 kappa
Other Names:
Programmed cell death protein 1, Pdcd1, CD279
Host:
Humanized
Species Reactivity:
Human
Specificity:
Detects human PD-1. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Nivolumab. This product is for research use only.
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.
Concentration:
1.0 – 5.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
Endotoxin:
≤ 0.75 EU/mg as determined by the LAL method
Storage:
Nivolumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Functional Assays
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
ichorbio’s nivolumab biosimilar is for research use only: it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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