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Home / Antibodies / Low Endotoxin
  • 2020 FDA Approvals Eculizumab
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2020 FDA Approvals Denosumab

Denosumab Biosimilar – Research Grade [ICH4019]

$704.00 – $4,080.00

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2020 FDA Approvals Denosumab
Denosumab Biosimilar – Research Grade [ICH4019]

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SKU: ICH4019 Categories: anti-human, Biosimilar Antibodies, Low Endotoxin
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Bulk Denosumab Biosimilar – Research Grade

Product Benefits:
ichorbio’s Denosumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Size:
ichorbio’s research grade denosumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg
ichorbio regularly manufactures bulk multi-gram amounts of our denosumab biosimilar – please contact us for pricing.
Target:
RANKL
Clone:
n/a
Isotype:
IgG2
Other Names:
Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254, Rank Ligand
Host:
Humanized
Species Reactivity:
Human
Specificity:
Detects human RANK Ligand. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Denosumab. This product is for research use only.
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Denosumab biosimilar is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.
Concentration:
1.0 – 5.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
Endotoxin:
≤ 0.75 EU/mg as determined by the LAL method
Storage:
Denosumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Functional Assays
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:

ichorbio’s denosumab biosimilar is for research use only: it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Size:

2mg, 5mg, 10mg, 20mg, 25mg, 50mg, 100mg

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About us

From Oxford, United Kingdom - ichorbio supplies the best antibodies for in vivo research. Our in vivo antibodies are sold for the purposes of research only, not for therapeutic or diagnostic use.

ichorbio Ltd, Grove Business Park, Downsview Road, Wantage OX12 9FF

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