Anti-Mouse CTLA-4 Antibody (9H10) – DyLight® 680 [ICH1084-680]
$90.00 – $263.00
Anti-Mouse CTLA-4 Antibody (9H10) – DyLight® 680
Product Benefits:
ichorbio’s Anti-Mouse CTLA-4 Antibody (9H10) – DyLight® 680 is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CTLA-4
Clone:
9H10
Isotype:
Syrian Hamster IgG
Other Names:
Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
Uniprot:
Host:
Syrian Hamster
Species Reactivity:
Mouse, Rat
Specificity:
Anti-Mouse CTLA-4 Antibody (9H10) – DyLight® 680 recognizes an epitope on Mouse CD152
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
CTLA-4 is expressed on activated T and B lymphocytes.
Background:
CD152, also known as CTLA-4 or Ly-56 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
Immunogen:
Purified Recombinant Mouse CTLA4
Concentration:
0.5 mg/ml
Formulation:
This DyLight® 680 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage:
This DyLight® 680 conjugate is stable when stored at 2-8°C. Do not freeze.
Applications:
Flow Cytometry, Western Blot
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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