ichorbio’s Anti-Mouse CD80 (16-10A1) – DyLight® 488 is manufactured in a cGMP compliant facility. ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information.
Anti-Mouse CD80 (16-10A1) – DyLight® 488 recognizes an epitope on Mouse CD80
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells.
CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
Purified Recombinant Mouse CD80 (>98%)
This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative..
This DyLight® 488 is stable when stored at 2-8°C. Do not freeze.
Flow Cytometry: This antibody can be used at a concentration of ≤ 0.25 µg per 100 µl of whole blood (or per 1.0 x 10^6 cells in a 100 µl total staining volume).Immunocytochemistry: Assay Dependent.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.