Skip to content
  • Login / Register
  • Cart / $0.00
    • No products in the cart.

  • Add anything here or just remove it...
ichorbioichorbio
  • Products
    • Immune Checkpoint Molecules
      • CD40 Reagents
      • CD70 Reagents
      • CD86 Reagents
      • CTLA-4 Reagents
      • LAG-3 Reagents
      • PD-1 Reagents
      • PD-L1 Reagents
    • Nucleic Acid Stains
    • Research Biosimilars – All Products
    • Isotype Controls
    • Type I & Type II Interferons
    • Ultra-Pure Detergents
    • Mouse Immune Cell Depletion Antibodies
  • About Us
  • Resources
    • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
    • Amazon Vouchers for Reviews
    • How to Write a Great Life Science Paper
  • Distribution Network
  • Contact Us
  • Cart

    No products in the cart.

Home / Applications / Flow Cytometry
Filter

Anti-Mouse CD318 In Vivo Antibody – Low Endotoxin (9a2) [ICH1165]

$320.00 – $2,378.00

Clear
Anti-Mouse CD318 In Vivo Antibody – Low Endotoxin (9a2) [ICH1165]

— OR —

SKU: ICH1165 Categories: anti-mouse, Flow Cytometry, Low Endotoxin, Ultra Low Endotoxin
Browse
  • Antibodies
    • Biosimilar Antibodies
    • Isotype Controls
    • Low Endotoxin
    • Ultra Low Endotoxin
  • Applications
    • Blocking
    • CODEX
    • CyTOF
    • Dot Blot
    • ELISA
    • ELISpot
    • Flow Cytometry
    • Flow Cytometry (intracellular)
    • Functional Assays
    • IHC (Frozen)
    • IHC (Paraffin)
    • ImmunoCytoChemistry
    • Immunofluorescence
    • Immunoprecipitation
    • In Situ Hybridization
    • In Vivo Depletion
    • IP-Mass Spectrometry
    • Neutralization
    • Western Blot
  • Conjugated
    • APC
    • Biotin
    • DyLight 488
    • DyLight 550
    • DyLight 594
    • DyLight 633
    • DyLight 650
    • DyLight 680
    • DyLight 755
    • DyLight 800
    • FITC
    • PE
    • PE/Cy7
    • PerCP
  • Gel Stain
  • Recombinant Proteins
  • Species Reactivity
    • anti-bovine
    • anti-chicken
    • anti-human
    • anti-mouse
    • anti-rat
    • Monkey
  • Description
  • Additional information
  • Reviews (0)

Bulk anti-CD318 In Vivo Antibody – Low Endotoxin (9a2)

 

Product Benefits:
ichorbio’s anti- CD318 In Vivo Antibody – Low Endotoxin (9a2) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CD318
Clone:
9a2
Isotype:
Mouse IgG2b κ
Other Names:
CDCP1, CUB domain-containing protein 1, SIMA135
Uniprot:
Q9H5V8
Host:
Mouse
Species Reactivity:
Human/Mouse
Specificity:
Clone 9A2 recognizes an epitope within the extracellular domain of human/mouse CDCP1
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
CDCP1 is widely expressed in the esophagus, skin, colon, duodenum, stomach and other tissues.
Background:
CDCP1 is a transmembrane glycoprotein of molecular weight 140 kDa. CDCP1 is a ligand for a receptor molecule (CD6) that is expressed on some T-cells and is thought to be involved in T-cell migration and chemotaxis. It has a large extracellular domain that includes two CUB domains, and a smaller intracellular domain. The smaller intracellular domain contains five tyrosine residues (Y707, Y734, Y743, Y762 and Y806). CDCP1 is cleaved next to Arg368 (at the extracellular domain) by serine proteases. This cleavage yields a truncated molecule with a molecular weight of 80 kDa.1 CDCP1 is not typically cleaved In vivo. However, its cleavage can be induced during tumorigenesis or tissue injury.2 CDCP1 acts as a substrate for Src family kinases which exclusively mediate the phosphorylation of CDCP1. In cultured cells, tyrosine phosphorylation of CDCP1 transpires when cells are stimulated to detach via trypsin or EDTA. This detachment is associated with the phosphorylation of CDCP1 along with the simultaneous dephosphorylation of focal adhesion proteins. Conversely, during cellular attachment, CDCP1 is dephosphorylated, while focal adhesion proteins are simultaneously phosphorylated. Furthermore, CDCP1 is suspected to play a role in autoimmune diseases such as encephalomyelitis, multiple sclerosis and inflammatory arthritis.3
Concentration:
1.0 mg/ml
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
IMPACT Pathogen Test:
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for:
Mycoplasma spp.
Mycoplasma pulmonis
Sendai virus
Mouse hepatitis virus
Pneumonia virus of mice
Minute virus of mice
Mouse parvovirus (MPV1-5)
Theiler’s murine encephalomyelitis virus
Murine norovirus
Reovirus 3
Mouse rotavirus
Ectromelia virus
Lymphocytic choriomeningitis virus
Polyoma virus
Lactate dehydrogenase-elevating virus
Mouse adenovirus (MAD1, MAD2)
Mouse cytomegalovirus
K virus
Mouse thymic virus
Hantaan virus
Corynebacterium bovis
Corynebacterium spp. (HAC2)
Storage:
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Flow Cytometry
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Size:

1mg, 5mg, 25mg, 50mg, 100mg

Endotoxin Level:

Low, Ultra low

Reviews

There are no reviews yet.

Be the first to review “Anti-Mouse CD318 In Vivo Antibody – Low Endotoxin (9a2) [ICH1165]” Cancel reply

Related products

+
Quick View

anti-mouse

Anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11) [ICH1041]

$320.00 – $2,378.00
+
Quick View

Isotype Controls

Mouse IgG1 Isotype Control for In Vivo – Low Endotoxin (HKSP) [ICH2247]

$320.00 – $2,378.00
+
Quick View

Isotype Controls

Mouse IgM Isotype Control for In Vivo – Low Endotoxin [ICH2252]

$320.00 – $2,378.00
+
Quick View

anti-human

Anti-CD20 In Vivo Antibody – Low Endotoxin (2H7) [ICH1012]

$320.00 – $2,378.00
About us

From Oxford, United Kingdom - ichorbio supplies the best antibodies for in vivo research. Our in vivo antibodies are sold for the purposes of research only, not for therapeutic or diagnostic use.

ichorbio Ltd, Grove Business Park, Downsview Road, Wantage OX12 9FF

Our best selling in vivo antibodies:

  • CTLA-4 in vivo antibody (9H10)
  • CTLA-4 in vivo antibody (9D9)
  • HLA-DP in vivo antibody (B7/21)
  • IFNAR1 in vivo antibody (MAR1-5A3)
  • PD-1 in vivo antibody (RMP1-14)
  • PD-L1 in vivo antibody (10F.9G2)
  • TNF-alpha in vivo antibody (TN3-19.12)

Our best selling Research Grade Biosimilars:

  • Atezolizumab - Research Grade
  • Avelumab - Research Grade
  • Eculizumab - Research Grade
  • Ipilimumab - Research Grade
  • Nivolumab - Research Grade
  • Ofatumumab - Research Grade
  • Pembrolizumab - Research Grade
  • A Beginner’s Guide to Writing a Life Science Paper
  • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
  • Terms & Conditions
  • Privacy Policy
Copyright 2021 © ichorbio .
  • Products
    • Immune Checkpoint Molecules
      • CD40 Reagents
      • CD70 Reagents
      • CD86 Reagents
      • CTLA-4 Reagents
      • LAG-3 Reagents
      • PD-1 Reagents
      • PD-L1 Reagents
    • Nucleic Acid Stains
    • Research Biosimilars – All Products
    • Isotype Controls
    • Type I & Type II Interferons
    • Ultra-Pure Detergents
    • Mouse Immune Cell Depletion Antibodies
  • About Us
  • Resources
    • Comparing ichorbio to Bio X Cell and BioLegend: Product Attributes
    • Amazon Vouchers for Reviews
    • How to Write a Great Life Science Paper
  • Distribution Network
  • Contact Us
  • Login

Login

Lost your password?

Register

A password will be sent to your email address.

Your personal data will be used to support your experience throughout this website, to manage access to your account, and for other purposes described in our privacy policy.

We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok