Anti-Mouse MAdCAM-1 In Vivo Antibody – Low Endotoxin (MECA-367) [ICH1123]
$378.00
Bulk anti-MAdCAM-1 In Vivo Antibody – Low Endotoxin (MECA-367)
Product Benefits:
ichorbio’s anti-MAdCAM-1 In Vivo Antibody – Low Endotoxin (MECA-367) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
MAdCAM-1
Clone:
MECA-367
Isotype:
Rat IgG2a
Other Names:
Mucosal addressin cell adhesion molecule 1
Host:
Rat
Species Reactivity:
Mouse
Specificity:
Anti-MAdCAM-1 In Vivo Antibody – Low Endotoxin (MECA-367) recognizes an epitope on Mouse MAdCAM-1
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a multifunctional type l transmembrane adhesion molecule that is expressed selectively at venular sites of lymphocyte extravasation into mucosal lymphoid tissues and lamina propria, where it directs local lymphocyte trafficking. MAdCAM-1 is involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract. MAdCAM-1 may be a relevant tissue-specific therapeutic target for the modulation of inflammatory bowel disease activity.
Immunogen:
Mouse Endothelial Cells
Concentration:
1.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
<1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
anti-MAdCAM-1 In Vivo Antibody – Low Endotoxin (MECA-367) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Flow Cytometry, IHC, Immunoprecipitation, Western Blot, Blocking, Immunofluorescence, Functional Assays
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control:
| Size: | |
|---|---|
| Endotoxin Level: | Low, Ultra low |
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