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Home / Applications / Flow Cytometry
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Anti-Mouse IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147) [ICH1117]

$320.00 – $2,140.00

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Anti-Mouse IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147) [ICH1117]

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SKU: ICH1117 Categories: anti-mouse, Blocking, Flow Cytometry, Immunoprecipitation, Low Endotoxin, Western Blot
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  • Antibodies
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    • Low Endotoxin
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    • Blocking
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    • anti-bovine
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Bulk anti-IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147)

 

Bio X Cell:

ICH1117 is up to 11% cheaper for academia & non-profits and up to 51% cheaper for industry than the equivalent product BE0256 from Bio X Cell.
We guarantee that our antibody will perform exactly the same in your experiments as BE0256 from Bio X Cell: if it doesn’t we will refund your purchase and pay for the Bio X Cell antibody to be delivered to you as soon as possible.

Product Benefits:
ichorbio’s anti-IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
IL1R1
Clone:
JAMA-147
Size:
ichorbio’s JAMA-147 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-IL-1R JAMA-147 clone – please contact us for pricing.
Isotype:
Armenian Hamster IgG
Other Names:
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha,
IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a
Uniprot:
P13504
Host:
Armenian Hamster
Species Reactivity:
Mouse
Specificity:
Anti-IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147) recognizes Mouse IL-1 R1
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
Immunogen:
Extracellular domain of mouse IL-1 R type 1
Concentration:
1.0 – 5.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
anti-IL-1R In Vivo Antibody – Low Endotoxin (JAMA-147) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles
Applications:
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control:
Armenian Hamster IgG Isotype Control for In Vivo – Low Endotoxin [PIP] (ICH2251)
Size:

1mg, 5mg, 25mg, 50mg, 100mg

Endotoxin Level:

Low, Ultra low

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About us

From Oxford, United Kingdom - ichorbio supplies the best antibodies for in vivo research. Our in vivo antibodies are sold for the purposes of research only, not for therapeutic or diagnostic use.

ichorbio Ltd, Grove Business Park, Downsview Road, Wantage OX12 9FF

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