Anti-Mouse CD54 In Vivo Antibody – Low Endotoxin (YN1/1.7.4) [ICH1059]
$320.00 – $2,378.00
Bulk anti-CD54 In Vivo Antibody – Low Endotoxin (YN1/1.7.4)
Bio X Cell:
ICH1059 is up to 11% cheaper for academia & non-profits and up to 51% cheaper for industry than the equivalent product BE0020-1 from Bio X Cell.
We guarantee that our antibody will perform exactly the same in your experiments as BE0020-1 from Bio X Cell: if it doesn’t we will refund your purchase and pay for the Bio X Cell antibody to be delivered to you as soon as possible.
Product Benefits:
ichorbio’s anti-CD54 In Vivo Antibody – Low Endotoxin (YN1/1.7.4) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CD54
Clone:
YN1/1.7.4
Size:
ichorbio’s YN1/1.7.4 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD54 YN1/1.7.4 clone – please contact us for pricing.
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD54 YN1/1.7.4 clone – please contact us for pricing.
Isotype:
Rat IgG2b
Other Names:
Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10
Uniprot:
Host:
Rat
Species Reactivity:
Mouse
Specificity:
Anti-CD54 In Vivo Antibody – Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Background:
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
Immunogen:
Mouse NS-1 cells
Concentration:
1.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
anti-CD54 In Vivo Antibody – Low Endotoxin (YN1/1.7.4) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), Immunoprecipitation
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control:
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