Anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11) [ICH1041]
$320.00 – $2,378.00
Bulk anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11)
Bio X Cell:
ICH1041 is up to 19% cheaper for academia & non-profits and up to 52% cheaper for industry than the equivalent products BE0001-1 (low endotoxin) and BP0001-1 (ultra-low endotoxin) from Bio X Cell.
We guarantee that our antibody will perform exactly the same in your experiments as BE/BP001-1 from Bio X Cell: if it doesn’t we will refund your purchase and pay for the Bio X Cell antibody to be delivered to you as soon as possible.
Product Benefits:
ichorbio’s anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11) is manufactured in a cGMP compliant facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CD3e
Clone:
145-2C11
Size:
ichorbio’s 145-2C11 in vivo antibody is available in the following bulk sizes:
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD3e 145-2C11 clone – please contact us for pricing.
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD3e 145-2C11 clone – please contact us for pricing.
Isotype:
Armenian Hamster IgG
Other Names:
T3/Leu-4 epsilon chain, CD3 epsilon chain, CD3e
Host:
Armenian Hamster
Species Reactivity:
Mouse
Specificity:
Anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11) recognizes an epitope on Mouse CD3e
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
The CD3 complex is present on thymocytes (differentiation dependent), mature T cells, NK-T cells of all mouse strains tested.
Background:
CD3e is a 20 kD transmembrane protein and is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Immunogen:
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Concentration:
1.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
IMPACT Pathogen Test:
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham’s rat virus
Toolan’s H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler’s murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham’s rat virus
Toolan’s H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler’s murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
Storage:
anti-CD3e In Vivo Antibody – Low Endotoxin (145-2C11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Immunoprecipitation, Blocking
Application Notes:
Blocking: The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells
Each investigator should determine their own optimal working dilution for specific applications.
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Related Antibody:
Antibodies against the same target:
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