Bulk anti-CD154 In Vivo Antibody – Low Endotoxin (MR1)
ICH1072 is up to 19% cheaper for academia & non-profits and up to 52% cheaper for industry than the equivalent products BE0017-1 (low endotoxin) and BP0017-1 (ultra-low endotoxin) from Bio X Cell.
We guarantee that our antibody will perform exactly the same in your experiments as BE/BP0017-1 from Bio X Cell: if it doesn’t we will refund your purchase and pay for the Bio X Cell antibody to be delivered to you as soon as possible.
1mg, 5mg, 25mg, 50mg and 100mg
ichorbio regularly manufactures multi-gram amounts of our anti-CD154 MR1 clone – please contact us for pricing.
CD154, also called CD40 ligand or CD40L, is a type II transmembrane glycoprotein belonging to the TNF receptor family that is primarily expressed on activated T cells and is a member of the TNF family of molecules. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
CD40 ligand is primarily expressed on activated CD4+ T lymphocytes but is also found in a soluble form. While CD40L was originally described on T lymphocytes, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages, basophils, NK cells, B lymphocytes, as well as non-haematopoietic cells (smooth muscle cells, endothelial cells, and epithelial cells).
Pneumonia virus of mice
Kilham’s rat virus
Toolan’s H1 virus
Minute virus of mice
Theiler’s murine encephalomyelitis virus