Anti-Mouse CD122 In Vivo Antibody – Low Endotoxin (TM-beta 1) [ICH1070]
$184.00
Bulk anti-CD122 In Vivo Antibody – Low Endotoxin (TM-beta 1)
Product Benefits:
ichorbio’s anti-CD122 In Vivo Antibody – Low Endotoxin (TM-beta 1) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CD122
Clone:
TM-beta 1
Isotype:
Rat IgG2b
Other Names:
Interleukin-2 receptor subunit beta, Il2rb, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, p70-75
Uniprot:
Host:
Rat
Species Reactivity:
Mouse
Specificity:
Anti-CD122 In Vivo Antibody – Low Endotoxin (TM-beta 1) recognizes an epitope on Mouse IL-2RB
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
T-Cells, B-cells, NK-cells, monocytes, and macrophages
Background:
CD122 is a 70-75 kD IL-2 receptor beta chain also known as IL-2RB, which is also shared by the IL-15 receptor. Clone TM-Beta1 (TM-B1) antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Immunogen:
Rat T-cell line expressing Mouse IL-2Rbeta
Concentration:
1.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
anti-CD122 In Vivo Antibody – Low Endotoxin (TM-beta 1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control:
| Size: | |
|---|---|
| Endotoxin Level: | Low, Ultra low |
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