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Infliximab Biosimilar - Research Grade
$315.00 - $19,890.00
Infliximab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
TNF alpha
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human TNF-alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Infliximab.
Shipping Conditions
Blue ice
Background
A pivotal pro-inflammatory cytokine, tumour necrosis factor alpha (TNF-α) is implicated across a broad range of autoimmune and inflammatory conditions studied preclinically. This research-grade anti-human TNF-α recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of infliximab, built around the TNF-α target for research use only. Manufactured to in vivo standards as an ultra-pure, low-endotoxin human IgG1-kappa, it is supplied in scalable milligram to gram quantities to serve high-throughput and bulk laboratories. The antibody acts as a consistent control and active reagent across in vitro neutralisation screening, in vivo inflammatory disease models, and biologics characterisation.
Other Names
Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Uniprot
P01375
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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