Evolocumab Biosimilar - Research Grade

Human

PCSK9

1.0 - 5.0 mg/ml

Human IgG2

Humanized

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Evolocumab.

Blue ice

By controlling degradation of the LDL receptor, proprotein convertase subtilisin/kexin type 9 (PCSK9) has become a prominent target in cardiovascular and lipid-metabolism research. This research-grade anti-human PCSK9 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of evolocumab, built around the PCSK9 target as a human IgG2 for research use only. Manufactured to in vivo standards as an ultra-pure, low-endotoxin preparation, it is supplied in scalable milligram to gram quantities for high-throughput and bulk laboratories. The antibody supports preclinical applications including PCSK9-blocking assays, in vitro LDL-receptor studies, and in vivo models of lipid metabolism.

Proprotein convertase subtilisin/kexin type 9, NARC-1, PC9

Q8NBP7

ICH3001-100ml ICH3002-100ml ICH3003-100ml

https://www.imgt.org/mAb-DB/