Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin

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SKU
ICH1069
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$400.00 - $2,945.00

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Mouse
Target
TNF Receptor I
Concentration
1.0 mg/ml
Isotype
Armenian Hamster IgG1
Host
Armenian Hamster
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Applications
Immunoprecipitation, Western Blot
Storage
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purification Method
This monoclonal antibody was purified using Protein A
Specificity
Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Shipping Conditions
Blue ice
Background
TNF Receptor I (CD120a, TNFR1) is the principal receptor mediating tumour necrosis factor signalling, driving inflammatory, apoptotic and survival pathways. Clone 55R-593 is an Armenian hamster IgG1 monoclonal antibody to mouse TNF Receptor I, validated for immunoprecipitation and Western blot. Anti-mouse CD120a 55R-593 is supplied in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. This non-therapeutic, research-use-only (RUO) reagent offers reproducible, lot-to-lot consistent performance for dissecting TNF signalling in mouse models.
Other Names
Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a
Clone
55R-593
Uniprot
P25118
Buffer
ICH3001-100ml ICH3002-100ml ICH3003-100ml
Antigen Distribution
Variety of cell types at low levels
Immunogen
E. coli-expressed extracellular domain of the mouse TNFRI protein
Aggregation
Aggregation level ≤ 5%
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