Back to Top
Ado-Trastuzumab Emtansine Biosimilar - Research Grade
$1,275.00 - $19,890.00
Ado-Trastuzumab Emtansine Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
HER2
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
Shipping Conditions
Blue ice
Background
An oncogenic receptor tyrosine kinase, HER2 (ERBB2) has long been a target for antibody and conjugate research. This research-grade reagent is an unconjugated, non-therapeutic analog of ado-trastuzumab emtansine, built around the HER2 target and intended strictly for research use only. Manufactured to in vivo standards as an ultra-pure, low-endotoxin human IgG1, it is supplied in scalable milligram to gram quantities to support high-throughput and bulk laboratories. The reagent is suited to preclinical applications such as HER2-binding and internalisation studies, in vitro screening, in vivo tumour models, and antibody-drug conjugate development.
Other Names
Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
Uniprot
P04626
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
Write Your Own Review
















