CD86 antibody for in vivo use

ichorbio supplies a one anti-CD86 antibody for in vivo use.

Low Endotoxin Antibodies to CD86

CD86 Background

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. Acts as a receptor for adenovirus subgroup B. ichorbio supplies a number of reagents for CTLA-4 research.